Club Atlético de San Luis, commonly known as Atlético San Luis, is a Mexican professional football club based in San Luis Potosí, replacing San Luis Potosí's Liga MX team San Luis FC after its relocation. San Luis was promoted to Liga MX in 2019.

After the Clausura 2013 season, San Luis F.C., San Luis Potosí's first division franchise, relocated to Tuxtla Gutiérrez and became Chiapas F.C., leaving the city without a first division team. Jacobo Payán, owner of Estadio Alfonso Lastras and one of the largest employers of this state, acquired Tiburones Rojos de Veracruz from Ascenso MX and relocated it to the city. This sale happened after La Piedad, who recently won promotion, relocated to Veracruz.

Albeit the identity confusion, Atlético is essentially a resurrection of San Luis Fútbol Club geographically and aesthetically speaking. This is clearly reflected in the new shield that keeps the traditional blue and gold colors of the State of San Luis Potosí, although in darker hues.