Club Universidad Nacional, A.C., commonly known as U.N.A.M. or simply Pumas, is a Mexican professional football club based in Mexico City. Founded on 6 August 1954 as Club Deportivo Universidad, the club represents the National Autonomous University of Mexico (U.N.A.M.) and play their home games at the Estadio Olímpico Universitario inside Ciudad Universitaria.

The club is one of the most popular clubs in Mexico. Domestically, Universidad Nacional has won 11 trophies: 7 Liga MX, 1 Copa MX, the Campeón de Campeones twice, as well as 1 Segunda División de México. In international club football, the club has won 3 CONCACAF Champions Leagues and 1 Copa Interamericana. The team is also known for their youth development system which has produced international players such as Hugo Sánchez, Manuel Negrete, Luis Flores, Miguel España, Claudio Suárez, Luis García, Alberto García Aspe, David Patiño, Jorge Campos, Gerardo Torrado, Efraín Juárez, Héctor Moreno, Pablo Barrera, Israel Castro, Eduardo Herrera and Jesús Gallardo.

Club Universidad Nacional was originally an amateur club of college students from UNAM's several schools and then developed into a professional team competing in the Mexican football league. It is now one of the biggest stadiums in all of Mexico. It has evolved into one of the most popular Mexican teams and have gained an international following.

The team's blue and gold colors were selected as a tribute to the University of Notre Dame, whose football coaches helped to develop an American-style football team at the university. The nickname was inspired by Roberto 'Tapatio' Mendez, who coached the team from 1946–64 and whose motivational speeches often compared his players to pumas. The nickname stayed with the public, and all the athletic teams representing the University have been called Pumas.

Their home ground is the Estadio Olímpico Universitario, the main venue of the 1968 Summer Olympics. It has a seating capacity of over 72,000. The stadium is situated within the campus which enables easy access by the students. The Pumas have training facilities within the campus but their main complex is the Cantera, located nearby.